VU6001966

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VU6001966

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2009052-76-8

VU6001966 (compound 15m) 是一种有效的可穿过血脑屏障的mGlu2 (代谢型谷氨酸受体 2)负变构调节剂，mGlu2 和 mGlu3 的IC₅₀分别为 78 nM 和 >30 μM。VU6001966 可用作 mGlu2 PET 的示踪剂。

生物活性

VU6001966 (compound 15m) is a potent and cross the blood-brain barriermGlu2 (metabotropic glutamate receptor 2)negative allosteric modulator withIC₅₀s of 78 nM and >30 μM for mGlu2 and mGlu3, respectively. VU6001966 can serve as an mGlu2 PET tracer^[1].

IC₅₀& Target^[1]

mGluR2

78 nM (IC₅₀)

mGluR3

>30 μM (IC₅₀)

分子量

326.33

Formula

C₁₇H₁₅FN₄O₂

CAS 号

2009052-76-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.