TASP0433864

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TASP0433864

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1431980-60-7

TASP0433864 是一种选择性的metabotropic glutamate 2 (mGlu2) 受体正向变构调节剂，对人和大鼠 mGlu2 受体的EC₅₀分别为 199 nM 和 206 nM。TASP0433864 具有抗精神紊乱活性。

生物活性

TASP0433864 is a selective positive allosteric modulator (PAM) ofmetabotropic glutamate 2 (mGlu2) receptorwithEC₅₀values of 199 nM and 206 nM against human and rat mGlu2 receptors, respectively. TASP0433864 has antipsychotic activity^[1].

IC₅₀& Target

hmGluR2

199 nM (EC₅₀)

rat mGluR2

206 nM (EC₅₀)

分子量

329.39

Formula

C₁₈H₂₃N₃O₃

CAS 号

1431980-60-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.