VU6010572

立即咨询

VU6010572

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2126784-39-0

VU6010572 是一种有效的选择性mGlu3负变构调制器，其IC₅₀为 245 nM。VU6010572 是高度 CNS 渗透剂。

生物活性

VU6010572 is a potent and selective mGlu3 negative allosteric modulator withIC₅₀of 245 nM. VU6010572 is highly CNS penetrant^[1]^[2].

IC₅₀& Target

mGluR3

245 nM (IC₅₀)

体内研究
(In Vivo)

VU6010572 (3 mg/kg; i.p.) shows robust efficacy^[1].
VU6010572 (3 mg/kg; i.p.; 45 minutes) produces lasting anxiolytic-like behavioral effects^[2].

Animal Model:	Rats^[2]
Dosage:	3 mg/kg
Administration:	I.p.; 45 minutes
Result:	Produced lasting anxiolytic-like behavioral effects.

分子量

339.36

Formula

C₂₀H₁₈FNO₃

CAS 号

2126784-39-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.