[D-Arg25]-Neuropeptide Y (human) ([D-Arg25] NPY) is aY₁receptorselective agonist. Neuropeptide Y (human) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity^[1].

[D-Arg25]-NPY (1 μM) reversibly hyperpolarizes the membrane potential of hypocretin cells by 9.9 ± 1.4 mV (data not shown; p< 0.01; n = 10^[2].

Intracerebroventricular (icv) administration of [D-Arg25]NPY stimulates food intake in freely-feeding rats^[3].

4271.68

C₁₈₉H₂₈₅N₅₅O₅₇S

YPSKPDNPGEDAPAEDMARYYSAL-{D-Arg}-HYINLITRQRY-NH2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.