PSB 0474

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PSB 0474

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

917567-60-3

PSB 0474 (3-phenacyl-UDP) 是一种选择性的、有效的P2Y₆受体激动剂，EC₅₀值为 70 nM。PSB 0474 抑制星形胶质细胞和小胶质细胞增殖，增加NO释放。PSB 0474 诱导星形胶质细胞凋亡 (apoptosis)。

生物活性	PSB 0474 (3-phenacyl-UDP) is a selective and potentP2Y₆receptor agonist with anEC₅₀of 70 nM^[1]. PSB 0474 inhibits cell proliferation, increases NO release in astrocytes and microglia cells. PSB 0474 induces astrocytesapoptosis^[2].
IC₅₀& Target	IC₅₀: 70 nM (P2Y₆)^[1]
分子量	522.29
Formula	C₁₇H₂₀N₂O₁₃P₂
CAS 号	917567-60-3
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.