8-Isoprostaglandin E2 (iPE2-III) 是异前列腺素类的一员。8-Isoprostaglandin E2 在体内作用于血栓素A2(TP) 受体,诱导血管收缩和血小板聚集。8-Isoprostaglandin E2 通过 cAMP 途径增强受体激活的 NFκB 配体(RANKL) 依赖的骨髓造血前体破骨潜能。
生物活性 | 8-Isoprostaglandin E2 (iPE2-III) is a member of the isoprostane class of prostanoids. 8-Isoprostaglandin E2 acts at the receptor forthromboxane A2(the TP) in vivo to induce vasoconstriction and platelet aggregation. 8-Isoprostaglandin E2 enhances receptor-activated NFkappa B ligand (RANKL)-dependent osteoclastic potential of marrow hematopoietic precursors via the cAMP pathway[1][2]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Powder | -20°C | 3 years | In solvent | -80°C | 6 months | | -20°C | 1 month |
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