SOS1 activator 1 (Compound 64) 是SOS1介导的核苷酸交换的激活剂，Kd为 44 nM。SOS1 是一种鸟嘌呤核苷酸交换因子，能与 Ras 蛋白结合，并使原来与 Ras 结合的 GDP 交换成GTP。可催化 GDP 与 RAS 上的 GTP 交换。
| 生物活性 | SOS1 activator 1 (Compound 64) is a potent activator ofSOS1-mediated nucleotide exchange with aKdof 44 nM. SOS1 is a guanine nucleotide exchange factor that catalyzes the exchange of GDP for GTP onRAS[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
