KRAS G12C inhibitor 43

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CAS NO:

2648808-69-7

KRAS G12C inhibitor 43 (compound 59) 是一种有效KRAS G12C抑制剂。KRAS G12C inhibitor 43 对 H358, A549, HCC 细胞具有抗迁移和抗增殖活性，IC₅₀s 分别为 0.001-1 μM, >1 μM, >1 μM。

生物活性

KRAS G12C inhibitor 43 (compound 59) is a potentKRAS G12Cinhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity withIC₅₀s of 0.001-1 μM, >1 μM, >1 μM for H358, A549, HCC cells ,respectively^[1].

IC₅₀& Target^[1]

KRas G12C

分子量

577.68

Formula

C₃₃H₃₅N₇O₃

CAS 号

2648808-69-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.