KRAS inhibitor-17 (compound 3-9) 是一种有效的KRAS G12C抑制剂，IC50为 3.37 μM。KRAS inhibitor-17 在 MIA PaCA-2，A549 细胞中的显示 p-ERK 抑制活性，IC50s 分别为 9.25，>33.3 μM。KRAS inhibitor-17 具有研究胰腺癌，结直肠癌和肺癌的潜力。
| 生物活性 | KRAS inhibitor-17 (compound 3-9) is a potentKRAS G12Cinhibitor with anIC50of 3.37 μM. KRAS inhibitor-17 shows p-ERK inhibition activities with IC50s of 9.25, >33.3 μM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-17 has the potential for the research of pancreatic, colorectal, and lung cancers[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
