6H05是突变型原癌基因K-ras(G12C)选择性变构抑制剂。
| 生物活性 | 6H05 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C).
IC50 value:
Target:K-RasG12C
6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous proteinH-Raswithout affecting wild-typeK-Ras[1]. 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors [2]. |
| IC50& Target[1] | |
| 分子量 | |
| Formula | |
| CAS 号 | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
