TLR9-IN-1 是一种有效且选择性的TLR9抑制剂，对人 TLR9 的IC50为 7 nM。TLR9-IN-1可用于研究不良免疫应答相关疾病。
| 生物活性 | TLR9-IN-1 is a potent and selectiveTLR9inhibitor with anIC50value of 7 nM for humanTLR9. TLR9-IN-1 can be used for researching diseases associated with undesirable immune response[1]. |
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体外研究
(In Vitro) | TLR9-IN-1 (compound no.29) (0-10 μM; 24 h) exhibits moderately inhibitory activity against IL-1b with an IC50of 1.61 μM in human monocytes (co-incubated with TLR8 agonist ORN8L, RNA oligonucleotide)[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
