TLR7/8 Antagonist 1 (Compound 16c) 是TLR7/8的有效拮抗剂，IC50值分别为 3.91 和 2.19 μM。TLR7/8 Antagonist 1 是一种咪唑喹啉衍生物化合物。Toll 样受体 (TLR) 7 和 8 是开发用于治疗传染病、癌症和自身免疫性疾病的免疫调节药物的关键靶点。
| 生物活性 | TLR7/8 Antagonist 1 (Compound 16c) is the potent antagonist ofTLR7/8withIC50s of 3.91 and 2.19 μM, respectively. TLR7/8 Antagonist 1 is an imidazoquinoline derivative compound. Toll-like receptors (TLRs) 7 and 8 are key targets in the development of immunomodulatory drugs for treating infectious disease,cancer, and autoimmune disorders[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
