(2R)-Mitiglinide-d5 calcium

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

(2R)-Mitiglinide-d5 (calcium) 是 Mitiglinide 氘代物。Mitiglinide (KAD-1229) 属于促胰岛素化合物，是一种 ATP 敏感的 K⁺通道 (K_ATPchannel) 拮抗剂。Mitiglinide 对 Kir6.2/SUR1 复合物 (胰腺-细胞 K_ATP通道) 具有高度特异性。Mitiglinide 可用于 2 型糖尿病的研究。

生物活性	(2R)-Mitiglinide-d5 (calcium) is deuterium labeled Mitiglinide. Mitiglinide (KAD-1229), an insulinotropic agent, is an ATP-sensitive K+ (KATP) channel antagonist. Mitiglinide is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide can be used for the research of type 2 diabetes^[1]^[2].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].
分子量	339.48
Formula	C₁₉H₁₉D₅NO₃.1/2Ca
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.