ICA 110381 (Compound 16) 是一种KCNQ2/Q3钾通道开放剂,有潜力用于癫痫的研究。ICA 110381 是KCNQ2/Q3激动剂 (EC50=0.38 μM) 以及KCNQ1拮抗剂 (IC50=15 μM)。
生物活性 | ICA 110381 (Compound 16) is aKCNQ2/Q3potassium channelopener for the treatment of epilepsy. ICA 110381 is aKCNQ2/Q3agonist (EC50=0.38 μM) as well asKCNQ1antagonist (IC50=15 μM)[1]. |
IC50& Target | EC50: 0.38 μM (KCNQ2/Q3 potassium channel)[1] IC50: 15 μM (KCNQ1)[1] |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |