Abiraterone-D4 (CB-7598-D4) is the deuterium labeled Abiraterone. Abiraterone is a potent and irreversibleCYP17A1inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of thecytochrome p450enzymeCYP17withIC₅₀s of 2.5 nM and 15 nM, respectively.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

353.53

C₂₄H₂₇D₄NO

2122245-62-7

阿比特龙 D4

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.