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Tauro-Obeticholic Acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tauro-Obeticholic Acid图片
CAS NO:863239-61-6

Tauro-Obeticholic acid 是牛磺酸的活性代谢物。Obeticholic Acid 是一种口服生物可利用的法尼样X受体 (FXR) 激动剂。
生物活性

Tauro-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist[1].

体外研究
(In Vitro)

Obeticholic acid is conjugated with taurine in the liver to form Tauro-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate Tauro-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces[1].

分子量

527.76

性状

Solid

Formula

C28H49NO6S

CAS 号

863239-61-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

 
 
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