IDO/TDO-IN-1

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IDO/TDO-IN-1

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CAS NO:

2033173-01-0

IDO/TDO-IN-1 (compound 25) 是一种高效的、具有口服活性的吲哚胺-2,3-双加氧酶(IDO)和色氨酸 2,3-双加氧酶(TDO)双重抑制剂，IC₅₀值分别为 9.7 nM 和 47 nM。

生物活性	IDO/TDO-IN-1 (compound 25) is a highly potent and orally active dualindoleamine-2,3-dioxygenase (IDO)andtryptophan 2,3-dioxygenase (TDO)inhibitor withIC₅₀s of 9.7 and 47 nM, respectively^[1].
IC₅₀& Target	IC50: 9.7 nM (Indoleamine-2,3-dioxygenase), 47 nM (Tryptophan 2,3-dioxygenase)^[1]
体外研究 (In Vitro)	IDO/TDO-IN-1 inhibits IDO in the Hela cell line with an IC₅₀of 76 nM^[1].
分子量	413.49
Formula	C₂₅H₂₄FN₅
CAS 号	2033173-01-0
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.