IDO1/TDO-IN-1

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IDO1/TDO-IN-1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2379527-72-5

IDO1/TDO-IN-1 (30) 是IDO1(非竞争性, K_i为 0.23 μM) andTDO(竞争性, K_i为 0.73 μM) 的双抑制剂。IDO1/TDO-IN-1 (30) 通过潜在的线粒体介导的Bcl-2/Bax通路显著促进细胞凋亡。

生物活性

IDO1/TDO-IN-1 (30) is a potent dualIDO1(uncompetitive, K_iof 0.23 μM) andTDO(competitive, K_iof 0.73 μM) inhibitor. IDO1/TDO-IN-1 (30) significantly promotes cellapoptosisthrough the potential mitochondria-mediated Bcl-2/Bax pathway^[1].

IC₅₀& Target^[1]

IDO1

0.23 μM (Ki)

TDO

0.73 μM (Ki)

分子量

364.35

Formula

C₂₁H₁₆O₆

CAS 号

2379527-72-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.