ZC0101 是一种有效的、具有口服活性的IDO1和TrxR双重抑制剂，IC50分别为 0.084 μM 和 7.98 μM。ZC0101 有效诱导癌细胞凋亡 (apoptosis) 和活性氧 (ROS) 积累。
| 生物活性 | ZC0101 is a potent, orally activeIDO1andTrxRdual inhibitor withIC50values of 0.084 μM and 7.98 μM, respectively. ZC0101 effectively inducesapoptosisandROSaccumulation incancercells[1]. |
| IC50& Target | IDO1 0.084 μM (IC50) | TrxR 7.98 μM (IC50) |
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体内研究
(In Vivo) | ZC0101 (60 mg/kg; p.o.; once) effectively suppresses IDO1 activity in vivo[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
