Spironolactone-d3 (SC9420-d3) is the deuterium labeled Spironolactone. Spironolactone (SC9420) is an orally activealdosteronemineralocorticoid receptorantagonist with anIC₅₀of 24 nM. Spironolactone is also a potent antagonist ofandrogen receptorwith anIC₅₀of 77 nM. Spironolactone promotesautophagyin podocytes^[1][2][3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

419.59

C₂₄H₂₉D₃O₄S

螺内酯 d3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.