Malonyl CoA 是脂肪酸生物合成的底物和脂肪酸氧化抑制剂。Malonyl CoA 也是线粒体肉碱棕榈酰转移酶1 (CPT)的可逆抑制剂。
| 生物活性 | Malonyl CoA is a substrate for fatty acid biosynthesis and an inhibitor of fatty acid oxidation. Malonyl CoA is also a reversible inhibitor ofmitochondrial carnitine palmitoyltransferase (CPT) 1[1][2]. |
| IC50& Target | Human Endogenous Metabolite |
|
体外研究
(In Vitro) | 丙二酰辅酶A (20 μM，6分钟) 抑制 MCF-7 细胞 CPT1 活性 (降低 75%)[2].
丙二酰辅酶A (0-3 μM) 抑制雌性大鼠肝线粒体中的 CPT1 活性[3].
|
| 分子量 | |
| Formula | |
| CAS 号 | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
