JG26 是ADAM17的抑制剂，其对 ADAM8、ADAM17、ADAM10 和 MMP-12 的IC50值分别为12 nM、1.9 nM、150 nM 和9.4 nM。
| 生物活性 | JG26 is anADAM17inhibitor, withIC50values of 12 nM, 1.9 nM, 150 nM and 9.4 nM forADAM8,ADAM17,ADAM10andMMP-12, respectively[1]. |
| IC50& Target[1] | ADAM17 1.9 nM (IC50) | ADAM8 12 nM (IC50) | ADAM10 150 nM (IC50) | MMP-9 >500000 nM (IC50) | MMP-8 240 nM (IC50) | MMP-9 1630 nM (IC50) | MMP-12 9.4 nM (IC50) | MMP14 19500 nM (IC50) |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
