| CAS NO: | 230954-09-3 |
| 生物活性 | CP-544439 is a potent and orally active matrix metalloproteinase-13(MMP-13)inhibitor with anIC50of 0.75 nM[1][2]. | ||||||||
| IC50& Target[2][1][1] |
| ||||||||
| 体内研究 (In Vivo) | In vivo studies using a hamster model, in which the cartilage collagen degradation was induced by intra-articular injection of recombinant human MMP-13, demonstrated that oral administration of CP-544439 inhibits degradation of the cartilage collagen with an ED50of 14 mg/kg and efficacious plasma concentrations ranging from 0.5 to 1.0 g/ml[1]. | ||||||||
| 分子量 | 410.42 | ||||||||
| Formula | C18H19FN2O6S | ||||||||
| CAS 号 | 230954-09-3 | ||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
| 维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024 |