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2-Ketoglutaric acid Sodium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
2-Ketoglutaric acid Sodium图片
CAS NO:22202-68-2

Alpha-Ketoglutaric acid Sodium
2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) 是三羧酸循环的中间产物,同时通过转胺氨作用与谷氨酸和谷氨酰胺代谢联系起来。
生物活性

2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor oftyrosinase(IC50=15 mM)[1][2].

IC50& Target[1]

Human Endogenous Metabolite

 

Microbial Metabolite

 

Tyrosinase

15 mM (IC50)

体外研究
(In Vitro)

2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning[1].
2-Ketoglutaric acid Sodium acts as precursor for the synthesis of amino acids and nucleotides[2].

分子量

168.08

Formula

C5H5NaO5

CAS 号

22202-68-2

结构分类
  • Ketones, Aldehydes, Acids
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

 
 
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