Calcium 2-Oxoglutarate

立即咨询

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

71686-01-6

Calcium 2-oxoglutarate 是 Krebs 循环中 ATP 或 GTP 产生的中间体。Calcium 2-oxoglutarate 还充当氮同化反应的主要碳骨架。Calcium 2-oxoglutarate 是酪氨酸酶(tyrosinase)的可逆抑制剂 (IC₅₀=15 mM)。

生物活性

Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor oftyrosinase(IC₅₀=15 mM)^[1]^[2].

IC₅₀& Target^[1]

Tyrosinase

15 mM (IC₅₀)

Microbial Metabolite

Human Endogenous Metabolite

体外研究
(In Vitro)

Calcium 2-oxoglutarate has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning^[1].
Calcium 2-oxoglutarate acts as precursor for the synthesis of amino acids and nucleotides^[2].

分子量

184.16

Formula

C₅H₄CaO₅

CAS 号

71686-01-6

结构分类

Ketones, Aldehydes, Acids

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.