AChE/MAO-B-IN-3 (Compound D30) 是AChE和MAO-B的抑制剂，对人AChE和MAO-B的IC50分别为 0.0257 μM 和 0.0456 μM。AChE/MAO-B-IN-3 可用于阿尔兹海默症的研究。
| 生物活性 | AChE/MAO-B-IN-3 (Compound D30) is a dualAChEandMAO-Binhibitor withIC50s of 0.0257 μM and 0.0456 μM against humanAChEandMAO-B, respectively. AChE/MAO-B-IN-3 can be used for the research of Alzheimer’s disease[1]. |
| IC50& Target[1] | Aβ42 0.0074 μM (IC50) | hAChE 0.0257 μM (IC50) | hMAO-B 0.0456 μM (IC50) |
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体外研究
(In Vitro) | AChE/MAO-B-IN-3 (Compound D30) 具有抗氧化活性，在 DPPH 自由基清除活性测试中的 IC50为 0.246 ± 0.011 μM[1]。
AChE/MAO-B-IN-3 抑制 β-淀粉样蛋白 1-42 (Aβ42)，IC50为0.1780 ± 0.0074 μM[1]。
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
