LSD1-IN-16 (compound 4b) 是一种有效的LSD1抑制剂。LSD1-IN-16 对LSD1-CoREST、MAO-A和MAO-B具有抑制作用,IC50值分别为 0.015、0.024 和 0.366 μM。LSD1-IN-16 在前列腺癌 LNCaP 细胞中显示细胞生长阻滞,IC50为 15.2 μM。
生物活性 | LSD1-IN-16 (compound 4b) is a potentLSD1inhibitor. LSD1-IN-16 can inhibitLSD1-CoREST,MAO-AandMAO-B, withIC50values of 0.015, 0.024, and 0.366 μM, respectively. LSD1-IN-16 displays cell growth arrest in prostatecancerLNCaP cells, with anIC50of 15.2 μM[1]. |
IC50& Target | MAO-A 0.024 ± μM (IC50) | MAO-B 0.366 ± μM (IC50) |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |