4-氨基水杨酸钠（4-氨基水杨酸钠盐二水合物）是目前用于耐多药结核病的抗分枝杆菌药物之一。
| Cas No. | 6018-19-5 |
| 别名 | 对氨基水杨酸钠; 4-Aminosalicylic acid sodium salt dihydrate |
| 化学名 | sodium;4-amino-2-hydroxybenzoate;dihydrate |
| Canonical SMILES | C1=CC(=C(C=C1N)O)C(=O)[O-].O.O.[Na+] |
| 分子式 | C7H7NO3.2H2O.Na |
| 分子量 | 211.15 |
| 溶解度 | ≥ 10.65mg/mL in DMSO |
| 储存条件 | 4°C, protect from light, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Sodium 4-aminosalicylate dihydrate is one of the antimycobacterial drugs currently used for multidrug-resistant tuberculosis. References:
[1]. Zheng J, et al. para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis. J Biol Chem. 2013 Aug 9;288(32):23447-56.
[2]. Sy SK, et al. N-acetyltransferase genotypes and the pharmacokinetics and tolerability of para-aminosalicylic acid in drug-resistant pulmonary tuberculosis patients. Antimicrob Agents Chemother. 2015 May 11. pii: AAC.04049-14. |
