氟苯尼考是一种常用的兽用抗生素，目前用于治疗牛呼吸道疾病，也用于水产养殖中控制鲶鱼肠道败血症。
| Cas No. | 73231-34-2 |
| 别名 | 氟苯尼考; (-)-Florfenicol; SCH-25298 |
| 化学名 | 2,2-dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide |
| Canonical SMILES | CS(=O)(=O)C1=CC=C(C=C1)C(C(CF)NC(=O)C(Cl)Cl)O |
| 分子式 | C12H14Cl2FNO4S |
| 分子量 | 358.21 |
| 溶解度 | ≥ 15.05mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Florfenicol, a commonly used veterinary antibiotic, is currently indicated for the treatment of bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g. References:
[1]. Al-Shahrani S, et al. Florfenicol induces early embryonic death in eggs collected from treated hens. BMC Vet Res. 2015 Aug 18;11(1):213.
[2]. Corinna Kehrenberg, et al. A new mechanism for chloramphenicol, florfenicol and clindamycin resistance: methylation of 23S ribosomal RNA at A2503. Molecular MicrobiologyVolume 57, Issue 4, pages 1064–1073, August 2005 |
