氯法齐明是一种亚氨基吩嗪染料，具有显着的抗炎作用，已与其他抗分枝杆菌药物联合用于治疗艾滋病和克罗恩病。
| Cas No. | 2030-63-9 |
| 别名 | 氯法齐明 |
| 化学名 | N,5-bis(4-chlorophenyl)-3-propan-2-yliminophenazin-2-amine |
| Canonical SMILES | CC(C)N=C1C=C2C(=NC3=CC=CC=C3N2C4=CC=C(C=C4)Cl)C=C1NC5=CC=C(C=C5)Cl |
| 分子式 | C27H22Cl2N4 |
| 分子量 | 473.4 |
| 溶解度 | ≥ 7mg/mL in DMSO with gentle warming |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Clofazimine is a fat-soluble iminophenazine dye, has a marked anti-inflammatory effect, has been used in combination with other antimycobacterial drugs to treat AIDS and Crohn's disease. References:
[1]. Arbiser JL, et al. Clofazimine: a review of its medical uses and mechanisms of action. J Am Acad Dermatol. 1995 Feb;32(2 Pt 1):241-7.
[2]. Cholo MC, et al. Clofazimine: current status and future prospects. J Antimicrob Chemother. 2012 Feb;67(2):290-8. |
