Glemanserin (MDL11939) 是有效和选择性5-HT2A受体的拮抗剂，对大鼠 5-HT2A、兔 5-HT2A和人 5-HT2A受体的Ki分别为 2.89、0.54 和 2.5 nM。
| 生物活性 | Glemanserin (MDL11939) is a potent and selective antagonist for serotonin receptor5-HT2A(Ki=2.89, 0.54 and 2.5 nM for rat 5-HT2A, rabbit 5-HT2Aand human 5-HT2A, respectively)[1][2]. |
体内研究
(In Vivo) | Glemanserin (MDL11939) suppresses Morphine-induced increase in locomotor activity, behavioral sensitization and withdrawal symptoms in male mice[1].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | | Powder | -20°C | 3 years | | 4°C | 2 years | | In solvent | -80°C | 6 months | | -20°C | 1 month |
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