JTE 013 是一种有效且特异性的 S1P2（Sphingosine-1-Phosphate 2；EDG-5）拮抗剂。 JTE 013 抑制放射性标记的 S1P 与人和大鼠 S1P2 的特异性结合，IC50 分别为 17 nM 和 22 nM。
| Cas No. | 383150-41-2 |
| 化学名 | N-(3,5-dichloropyridin-4-yl)-2-(1,3-dimethyl-4-propyl-1H-pyrazolo[3,4-b]pyridin-6-yl)hydrazinecarboxamide |
| Canonical SMILES | ClC1=C(C(Cl)=CN=C1)NC(NNC2=CC(CCC)=C3C(N(C)N=C3C)=N2)=O |
| 分子式 | C17H19N7OCl2 |
| 分子量 | 408.29 |
| 溶解度 | DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
