Anticancer agent 59 (compound 11) 对多种癌细胞具有抑制活性，特别是在 A549 细胞中 (IC50= 0.2 μM)，Anticancer agent 59 诱导肿瘤细胞凋亡，也诱导 Ca2+和ROS水平升高，能显著降低线粒体膜电位。Anticancer agent 59 在 A549 异种移植小鼠模型中能显著抑制肿瘤生长。
| 生物活性 | Anticancer agent 59 (compound 11) has inhibitory activity against kinds ofcancercell lines, especially in A549 withIC50of 0.2 μM. Anticancer agent 59 inducesapoptosisand an increase of Ca2+andROSincancercells. Anticancer agent 59 significantly decreases mitochondrial membrane potential. Anticancer agent 59 can suppress tumor growth in A549 mouse xenograft model[1]. |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
