EPQpYEEIPIYL

立即咨询

EPQpYEEIPIYL

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

147612-86-0

EPQpYEEIPIYL 是一种磷酸肽，是 Src 同源 2 (SH2) 结构域配体。 EPQpYEEIPIYL 通过与 SH2 域结合来激活 Src 家族成员 (例如 Lck，Hck，Fyn)。

生物活性

EPQpYEEIPIYL, a phosphopeptide, is aSrchomology 2 (SH2) domain ligand. EPQpYEEIPIYL activatesSrcfamily members (e.g. Lck, Hck, Fyn) by binding to SH2 domains^[1]^[2].

体外研究
(In Vitro)

The hmT-derived phosphopeptide, pY324, which has the sequence EPQpYEEIPIYL, shows the highest affinity binding to GST fusion proteins of the Lck SH2 domain (5-fold higher than Lck’s affinity-for the Lck tail phosphopeptide) and the Src SH2 domain (44-fold higher than Src’s affinity for the Src tail phosphopeptide)^[1].

分子量

1473.52

性状

Solid

Formula

C₆₆H₉₇N₁₂O₂₄P

CAS 号

147612-86-0

Sequence Shortening

EPQpYEEIPIYL

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据

In Vitro:

H₂O : 2 mg/mL(1.36 mM;ultrasonic and adjust pH to 2 with HCl)

配制储备液

浓度溶剂体积质量

1 mg

5 mg

10 mg

1 mM	0.6786 mL	3.3932 mL	6.7865 mL
5 mM	---	---	---
10 mM	---	---	---

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。