VEGFR-2-IN-13

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VEGFR-2-IN-13

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

VEGFR-2-IN-13 (Compound 19a) 是一种有效的VEGFR-2抑制剂，IC₅₀为 3.4 nM。VEGFR-2-IN-13 阻滞 HepG2 细胞周期的 G2/M 期，诱导细胞凋亡 (apoptosis)。

生物活性

VEGFR-2-IN-13 (Compound 19a) is a potentVEGFR-2inhibitor with anIC₅₀of 3.4 nM. VEGFR-2-IN-13 disrupts the HepG2 cell cycle by arresting the G2/M phase and inducesapoptosis^[1].

IC₅₀& Target

VEGFR2

3.4 nM (IC₅₀)

体外研究
(In Vitro)

VEGFR-2-IN-13 (Compound 19a) shows anti-proliferative activities with IC₅₀values of 8.2 μM and 5.4 μM against MCF-7 and HepG2 cells, respectively^[1].

分子量

454.50

Formula

C₂₄H₁₈N₆O₂S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.