GW768505A free base 是高效的VEGFR2 (KDR)和Tie-2双抑制剂，对 VEGFR2 作用的 pIC50值为 7.81。GW768505A free base 具有抗血管生成活性。
| 生物活性 | GW768505A free base is a potent dual inhibitor ofVEGFR2 (KDR)andTie-2, with a pIC50of 7.81 for VEGFR2. GW768505A free base has anti-angiogenic activity[1]。 |
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体外研究
(In Vitro) | GW768505A free base has inhibition for cancer cells growth in NCI-60 panel screening[2].
GW768505A free base is an inhibitor of KDR and TIE2, shows potent inhibition (71–88% inhibition at 100 nM) of the tropomysin-related kinases TRKA, TRKB and TRKC[2].
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| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
