VEGFR-2-IN-15

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VEGFR-2-IN-15

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

VEGFR-2-IN-15 (Compound 14b) 是一种有效的VEGFR-2抑制剂。VEGFR-2-IN-15 抑制 HepG2 细胞在 Pre-G1 期的生长，诱导细胞凋亡 (apoptosis)。

生物活性

VEGFR-2-IN-15 (Compound 14b) is a potentVEGFR-2inhibitor. VEGFR-2-IN-15 arrests the HepG2 cell growth at the Pre-G1 phase and inducesapoptosis^[1].

IC₅₀& Target

VEGFR2

体外研究
(In Vitro)

VEGFR-2-IN-15 (Compound 14b) shows cytotoxic activities with IC₅₀values of 4.754 ± 0.21 μM and 4.61 ± 0.34 μM against MCF-7 and HepG2 cells, respectively^[1].
VEGFR-2-IN-15 shows the highest activities with VEGFR-2 protein concentrations of 705.7 pg/ml^[1].

分子量

467.92

Formula

C₂₃H₁₈ClN₃O₄S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.