VEGFR-2-IN-24

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VEGFR-2-IN-24

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2455414-26-1

VEGFR-2-IN-24 是一种有效的VEGFR-2抑制剂，IC₅₀值为 0.22 μM。VEGFR-2-IN-24 可用于肿瘤研究。

生物活性

VEGFR-2-IN-24 is a potentVEGFR-2inhibitor withIC₅₀value of 0.22 μM. VEGFR-2-IN-24 can be used for tumor research^[1].

IC₅₀& Target^[1]

VEGFR2

0.22 μM (IC₅₀)

体外研究
(In Vitro)

VEGFR-2-IN-24 (Compound 8f) (0-1000 μM, 72 hours; human tumor cell lines) exerts the most potent antitumor activities against human cancer cell lines^[1].
VEGFR-2-IN-24 (Compound 8f) (0-1000 μM, 72 hours; human tumor cell lines) displays the highest anticancer activities withIC₅₀values of 11.19, 8.99 and 7.10 μM for HepG2, HCT-116 and MCF-7 cell lines, respectively^[1].
VEGFR-2-IN-24 (Compound 8f) (0-300 μg/mL, 5 min) remarkably exhibits VEGFR-2 inhibition withIC₅₀value of 0.22 μM^[1].

Cell Cytotoxicity Assay^[1]

Cell Line:	Hepatocellular carcinoma (HepG2), breast cancer (MCF-7) and colorectal carcinoma (HCT-116).
Concentration:	0.1, 10, 100 and 1000 μM
Incubation Time:	72 hours
Result:	Inhibited withIC₅₀values of 11.19, 8.99 and 7.10 μM for HePG-2, MCF-7 and HCT-116, respectively.

分子量

529.56

Formula

C₂₈H₂₃N₃O₆S

CAS 号

2455414-26-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.