Guanosine 5'-diphosphate

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CAS NO:

146-91-8

GDP

Guanosine 5'-diphosphate (GDP) 是一种核苷二磷酸，可激活 5'-三磷酸腺苷敏感的K⁺通道。Guanosine 5'-diphosphate 是一种潜在的铁动员剂，可阻断铁调素-铁转运蛋白 (hepcidin-ferroportin) 相互作用并调节IL-6/stat-3通路。Guanosine 5'-diphosphate 可用于炎症研究，如炎症性贫血 (AI)。

生物活性

Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitiveK⁺channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents thehepcidin-ferroportininteraction and modulates theinterleukin-6 (IL-6)/stat-3pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI)^[1]^[2].

IC₅₀& Target^[2]

Human Endogenous Metabolite

Clinical Trial

分子量

443.20

Formula

C₁₀H₁₅N₅O₁₁P₂

CAS 号

146-91-8

结构分类

Ketones, Aldehydes, Acids

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.