Adenosine 5'-diphosphate

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CAS NO:

58-64-0

Adenosine diphosphate
ADP

Adenosine 5'-diphosphate (Adenosine diphosphate) 是核苷二磷酸，是 ATP 酶对 ATP 去磷酸化的产物。Adenosine 5'-diphosphate 通过在 P_2T-嘌呤受体上的作用诱导人血小板聚集并抑制刺激的腺苷酸环化酶。

生物活性

Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulatedadenylate cyclaseby an action at P_2T-purinoceptors.

IC₅₀& Target

Human Endogenous Metabolite

体外研究
(In Vitro)

Adenosine 5'-diphosphate consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. Adenosine 5'-diphosphate is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division.

Clinical Trial

分子量

427.20

性状

Solid

Formula

C₁₀H₁₅N₅O₁₀P₂

CAS 号

58-64-0

结构分类

Ketones, Aldehydes, Acids

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据

In Vitro:

H₂O : 50 mg/mL(117.04 mM;Need ultrasonic)

配制储备液

浓度溶剂体积质量

1 mg

5 mg

10 mg

1 mM	2.3408 mL	11.7041 mL	23.4082 mL
5 mM	0.4682 mL	2.3408 mL	4.6816 mL
10 mM	0.2341 mL	1.1704 mL	2.3408 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (protect from light)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.
请依序添加每种溶剂： PBS
Solubility: 100 mg/mL (234.08 mM); Clear solution; Need ultrasonic and warming and heat to 60℃

*以上所有助溶剂都可在本网站选购。