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MAHMA NONOate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MAHMA NONOate图片
CAS NO:146724-86-9
包装与价格:
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A NO donor

Cas No.146724-86-9
别名Methylamine hexamethylene methylamine NONOate
化学名(Z)-1-[N-Methyl-N-[6-(N-methylammoniohexyl)amino]]diazen-1-ium-1,2-diolate
Canonical SMILESC[N+]([H])([H])CCCCCCN(N(N=O)[O-])C
分子式C8H20N4O2
分子量204.3
溶解度Soluble in water highly
储存条件Store at -80℃,protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

MAHMA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 1 minute and 3 minutes at 37℃ and 22-25℃, respectively, (pH 7.4) to liberate 2 moles of NO per mole of parent compound.[1],[2]

Reference:
[1]. Hrabie, J.A., Klose, J.R., Wink, D.A., et al. New nitric oxide-releasing zwitterions derived from polyamines The Journal of Organic Chemistry 58, 1472-1476 (1993).
[2]. Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms Methods in Enzymology 268, 281-293 (1996).

 
 
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