Picrasidine I

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Picrasidine I

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

100234-59-1

Picrasidine I 是一种抗炎和抗破骨细胞二聚生物碱，可以从苦木中分离出来。Picrasidine I 通过诱导细胞周期阻滞并下调ERK和Akt通路触发细胞凋亡。Picrasidine I 抑制MAPKs，NF-κB和ROS生成的激活，并抑制 c-Fos 和 NFATc1 的表达。

生物活性	Picrasidine I is an anti-inflammatory and anti-osteoclastogenic dimeric alkaloid that can be isolated fromPicrasma quassioides. Picrasidine I inducs cell cycle arrest, and triggers cellapoptosisby downregulatsERKandAktpathways. Picrasidine I inhibits the activation ofMAPKs,NF-κBandROSgeneration, and suppresses the expression of c-Fos and NFATc1^[1]^[2].
分子量	240.26
Formula	C₁₄H₁₂N₂O₂
CAS 号	100234-59-1
结构分类	Alkaloids Indole Alkaloids
来源	Plants Simaroubaceae Quassia amaraL.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.