Allyl methyl trisulfide

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CAS NO:

34135-85-8

Allyl methyl trisulfide 是一种挥发性有机化合物，是大蒜(Allium sativum L.)精油的成分，具有抗菌、抗氧化以及抗肿瘤活性等。

生物活性

Allyl methyl trisulfide is a volatile organic compound and a component of garlic (Allium sativum L.) essential oil, which has antibacterial, antioxidant and antitumor activities^[1].

体内研究
(In Vivo)

Allyl methyl trisulfide(AMS)(50-200 mg/kg, orally, daily, 30 days)在 STZ 诱导的高血糖大鼠中具有保护功效。可以导致血糖和促炎标志物 TNF-α、IL-6、NF-κB p65 表达显著降低，而血浆胰岛素水平升高，并且具有一定的抗氧化活性^[1]。

Animal Model:	Male Wistar rats (170-190 g)^[1]
Dosage:	50, 100 and 200 mg/kg
Administration:	orally in the daily morning for 30 days
Result:	Enhanced body, organ weight and reduced food, water intake. Dose-dependently decreased plasma glucose and enhanced insulin. Attenuated the oxidative stress stimulated by STZ in hepatocytes. Increased activity of hepatotoxicity markers AST, ALT and ALP. Significantly downregulated the expression of pro-inflammatory proteins, cytokines (TNF-α and IL-6) and transcription factors (NF-κB p65).

分子量

152.30

Formula

C₄H₈S₃

CAS 号

34135-85-8

来源

Plants
Amaryllidaceae
Allium sativumL.

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.