Norswertianin, a xanthone compound, serves as a powerfulanti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependentautophagy^[1].

Norswertianin (12.5-50 μM; 48 hours) stimulats expression of GFAP and β-tubulin in U251 cells^[1].
Norswertianin (40 μM; 48 hours) causes the appearance of elongated processes in U251 cells, associated with G2/M cell cycle arrest^[1].
Norswertianin (40 μM; 48 hours) exhibits an increase in intracellular acidification and LC3 conversion^[1].

260.20

C₁₃H₈O₆

22172-15-2

• Phenols
• Polyphenols

• Phenols
• Xanthones

• Plants
• Gentianaceae
• Swertia bimaculata(Sieb. et Zucc.) Hook. f. et Thoms. ex C. B. Clark

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.