硫酸卷曲霉素是一种肽类抗生素，通常与氨基糖苷类一起使用，与其他抗生素联合用于治疗耐多药结核病。
| Cas No. | 1405-37-4 |
| 别名 | 硫酸卷曲霉素 |
| Canonical SMILES | O=C([C@]([H])(C)NC([C@](N)([H])CNC1=O)=O)N[C@@]([H])(CNC(CC(CCCN)N)=O)C(NC(C(N[C@@]1([H])[C@@H]2CCNC(N)=N2)=O)=CNC(N)=O)=O.[xH2SO4] |
| 分子式 | C25H44N14O7.H2SO4 |
| 分子量 | 750.78 |
| 溶解度 | ≥ 251.8mg/mL in Water,<7.51mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Capreomycin sulfate is a peptide antibiotic, commonly grouped with the aminoglycosides, which is given in combination with other antibiotics for MDR-tuberculosis.IC50 value:Target: The drug should not be given with streptomycin or other drugs that may damage the auditory vestibular nerve. Patients on this drug will often require audiology tests. It is a cyclic peptide.Capreomycin is administered intramuscularly and shows bacteriostatic activity. References:
[1]. Johansen SK, et al. Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2'-O-methylations in 16S and 23S rRNAs. Mol Cell. 2006 Jul 21;23(2):173-82. |
