Benzydamine HCl 是一种局部作用的非甾体抗炎药，具有局部麻醉和镇痛作用；选择性结合前列腺素合成酶，具有显着的体外抗菌活性。
| Cas No. | 132-69-4 |
| 别名 | 盐酸苄达明 |
| 化学名 | 3-(1-benzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine;hydrochloride |
| Canonical SMILES | CN(C)CCCOC1=NN(C2=CC=CC=C21)CC3=CC=CC=C3.Cl |
| 分子式 | C19H23N3O.HCl |
| 分子量 | 345.87 |
| 溶解度 | ≥ 17.05mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Benzydamine hydrochloride is a locally-acting nonsteroidal anti-inflammatory drug with local anaesthetic and analgesic properties; selectively binds to prostaglandin synthetase and has notable in vitro antibacterial activity. References:
[1]. Anand JS, et al. Recreational abuse with benzydamine hydrochloride (tantum rosa). Clin Toxicol (Phila). 2007;45(2):198-9.
[2]. Opaleye ES, et al. Recreational use of benzydamine as a hallucinogen among street youth in Brazil. Rev Bras Psiquiatr. 2009 Sep;31(3):208-13.
[3]. Mota DM, et al. Use abusive of benzydamine in Brazil: an overview in pharmacovigilance. Cien Saude Colet. 2010 May;15(3):717-24.
[4]. Fanaki NH, et al. Antimicrobial activity of benzydamine, a non-steroid anti-inflammatory agent. J Chemother. 1992 Dec;4(6):347-52. |
