硫酸安普霉素是一种由 Streptomyces tenebrarius 菌株生产的氨基糖苷类抗生素，用于兽医实践。
| Cas No. | 65710-07-8 |
| 别名 | 硫酸安普霉素; Nebramycin II sulfate |
| 化学名 | (2R,3R,4S,5S,6S)-2-[[(2R,3S,4R,4aR,6S,7R,8aS)-7-amino-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-4-hydroxy-3-(methylamino)-2,3,4,4a,6,7,8,8a-octahydropyrano[3,2-b]pyran-2-yl]oxy]-5-amino-6-(hydroxymethyl)oxane-3,4-diol;sulfuric acid |
| Canonical SMILES | CNC1C(C2C(CC(C(O2)OC3C(CC(C(C3O)O)N)N)N)OC1OC4C(C(C(C(O4)CO)N)O)O)O.OS(=O)(=O)O |
| 分子式 | C21H41N5O11.xH2O4S |
| 分子量 | 637.66 |
| 溶解度 | ≥ 64.2mg/mL in Water,<6.38mg/mL in DMSO |
| 储存条件 | Store at 2-8℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Apramycin sulfate is an aminoglycoside antibiotic mproduced by a strain of Streptomyces tenebrarius, used in veterinary practice. References:
[1]. O'Connor S, et al. Apramycin, a unique aminocyclitol antibiotic. J Org Chem. 1976 Jun 11;41(12):2087-92.
[2]. Hunter JE, et al. Apramycin resistance plasmids in Escherichia coli: possible transfer to Salmonella typhimurium in calves. Epidemiol Infect. 1992 Apr;108(2):271-8.
[3]. Paget E, et al. Apramycin resistance as a selective marker for gene transfer in mycobacteria. J Bacteriol. 1996 Nov;178(21):6357-60 |
