Albicanol

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Albicanol

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

54632-04-1

Albicanol 是一种倍半萜类化合物，具有强大的抗氧化和对抗重金属毒性的活性。Albicanol 显示出细胞毒性。Albicanol 抑制profenofos (HY-B0832) 诱导的草鱼肝细胞遗传毒性^[1]。

生物活性

Albicanol is a sesquiterpenoid with potent antioxidant and antagonistic activities against heavy metal toxicity. Albicanol shows cytotoxicity. Albicanol suppressprofenofos(HY-B0832) induced genotoxicity in grass carp hepatocytes^[1]^[2].

体外研究
(In Vitro)

Albicanol (compound 6) (0-30 μM; 48 h) 显示细胞毒性，对 A549、MCF7、HepG2 细胞的 IC₅₀值分别 >30、24.14、>30 μM^{[1 ]}.
Albicanol (0.00005 μg/mL; 24 h) 显着抑制 L8824 细胞因 PFF 暴露而产生的遗传毒性^[2]。

Cell Cytotoxicity Assay^[1]

Cell Line:	A549, MCF7, HepG2 cells
Concentration:	0-30 μM
Incubation Time:	48 h
Result:	Showed cytotoxicity with IC₅₀s of >30, 24.14, >30 μM for A549, MCF7, HepG2 cells, respectively.

分子量

222.37

Formula

C₁₅H₂₆O

CAS 号

54632-04-1

结构分类

Others

来源

Plants
Dryopteridaceae
Dryopteris fragrans(L.) Schott

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.