| Cas No. | 204140-01-2 |
| 化学名 | 4-([1,1'-biphenyl]-4-ylcarbonyl)-N-hydroxy-1-[(4-methoxyphenyl)sulfonyl]-2-piperazinecarboxamide |
| Canonical SMILES | O=C(N1CCN(S(C2=CC=C(OC)C=C2)(=O)=O)C(C(NO)=O)C1)C(C=C3)=CC=C3C4=CC=CC=C4 |
| 分子式 | C25H25N3O6S |
| 分子量 | 495.6 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 25 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | MMP-9/MMP-13 inhibitor I is a cell-permeable inhibitor of matrix metalloproteinases (MMPs) that most potently inhibits MMP-9 and MMP-13 (IC50s = 0.9 nM for both). It less effectively inhibits MMP-1, MMP-3, and MMP-7 (IC50s = 43, 23, and 920 nM, respectively). MMP-9/MMP-13 inhibitor I has been used to elucidate the roles of MMPs in biological systems, including tumor cell invasion and pathogenesis of P. falciparum. |
