拉米夫定 (BCH-189) 是一种具有口服活性的核苷类逆转录酶抑制剂 (NRTI)。
| Cas No. | 134678-17-4 |
| 别名 | 拉米夫定; BCH-189 |
| 化学名 | 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one |
| Canonical SMILES | C1C(OC(S1)CO)N2C=CC(=NC2=O)N |
| 分子式 | C8H11N3O3S |
| 分子量 | 229.26 |
| 溶解度 | ≥ 10.5mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Lamivudine (BCH-189) is a nucleoside reverse transcriptase inhibitors (NRTIs). Lamivudine (BCH-189) can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. References:
[1]. Li, Y.C., [A clinical study on lamivudine treatment for advanced schistosomisis with chronic B hepatits]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi, 2013. 25(5): p. 548-9, 551.
[2]. Zhang, C.E., et al., [Effects of lamivudine on growth of intestinal characteristic bacteria by microcalorimetry in vitro]. Yao Xue Xue Bao, 2013. 48(10): p. 1590-4. |
